Seasonal influenza and vaccine herd effect
نویسنده
چکیده
The seasonal influenza vaccine programs in many regions aimed to protect most vulnerable population, but current trivalent influenza vaccine does not provide sufficient effectiveness among people under high risk for severe outcome of the influenza. The vaccine herd effect (VHE) is the extra protection of non-immune high risk persons, with increase of immunity among vaccinated healthier persons which prevents circulation of influenza in the community. Accumulating evidences are supporting the immunization of extended population with regard to the VHE.
منابع مشابه
An approximation of herd effect due to vaccinating children against seasonal influenza – a potential solution to the incorporation of indirect effects into static models
BACKGROUND Indirect herd effect from vaccination of children offers potential for improving the effectiveness of influenza prevention in the remaining unvaccinated population. Static models used in cost-effectiveness analyses cannot dynamically capture herd effects. The objective of this study was to develop a methodology to allow herd effect associated with vaccinating children against seasona...
متن کاملImpact of cross-protective vaccines on epidemiological and evolutionary dynamics of influenza.
Large-scale immunization has profoundly impacted control of many infectious diseases such as measles and smallpox because of the ability of vaccination campaigns to maintain long-term herd immunity and, hence, indirect protection of the unvaccinated. In the case of human influenza, such potential benefits of mass vaccination have so far proved elusive. The central difficulty is a considerable v...
متن کاملIncreasing herd immunity with influenza revaccination.
Seasonal influenza is a significant public health concern globally. While influenza vaccines are the single most effective intervention to reduce influenza morbidity and mortality, there is considerable debate surrounding the merits and consequences of repeated seasonal vaccination. Here, we describe a two-season influenza epidemic contact network model and use it to demonstrate that increasing...
متن کاملPositive Network Assortativity of Influenza Vaccination at a High School: Implications for Outbreak Risk and Herd Immunity
Schools are known to play a significant role in the spread of influenza. High vaccination coverage can reduce infectious disease spread within schools and the wider community through vaccine-induced immunity in vaccinated individuals and through the indirect effects afforded by herd immunity. In general, herd immunity is greatest when vaccination coverage is highest, but clusters of unvaccinate...
متن کاملDetermination of Seasonal Influenza Vaccination Acceptation Rate and Assessment of Knowledge and Attitude of Physicians and Personnel of Ali-Asghar Children’s Hospital
Background: Influenza is an acute respiratory viral infectious disease that can cause 650,000 deaths annually. Hospital personnel are highly exposed to it. Attention should be paid to the fact that these people, along with the risk to themselves, spread the infection among other patients and vulnerable groups’ like pediatric patients. The best way to prevent the disease is vaccination, which ha...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2014